Altered carnitine homeostasis is associated with decreased mitochondrial function and altered nitric oxide signaling in lambs with pulmonary hypertension

Utilizing aortopulmonary vascular graft placement in the fetal lamb, we have developed a model (shunt) of pulmonary hypertension that mimics congenital heart disease with increased pulmonary blood flow. Our previous studies have identified a progressive development of endothelial dysfunction in shun...

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Main Authors: Sharma, Shruti, Sud, Neetu, Wiseman, Dean A., Carter, A. Lee, Kumar, Sanjiv, Hou, Yali, Rau, Thomas, Wilham, Jason, Harmon, Cynthia, Oishi, Peter, Fineman, Jeffrey R., Black, Stephen M.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3970936/
https://ncbi.nlm.nih.gov/pubmed/18024721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00247.2007
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