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Structural insights into the SENP6 Loop1 structure in complex with SUMO2

The SENP proteases regulate the SUMO conjugates in the cell by cleaving SUMO from target proteins. SENP6 and SENP7 are the most divergent members of the SENP/ULP protease family in humans by the presence of insertions in their catalytic domains. Loop1 insertion is determinant for the SUMO2/3 activit...

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Autors principals: Alegre, Kamela O, Reverter, David
Format: Artigo
Idioma:Inglês
Publicat: Wiley-Blackwell 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3970894/
https://ncbi.nlm.nih.gov/pubmed/24424631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2425
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