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Sphingosine‐1‐phosphate acts as a key molecule in the direct mediation of renal fibrosis
The major sphingolipid metabolite, sphingosine‐1‐phosphate (S1P), has important biological functions. S1P serves as a ligand for a family of five G‐protein‐coupled receptors with distinct signaling pathways regulating important biological pathways. S1P induces renal fibrosis through an inflammatory...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Wiley Periodicals, Inc.
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3970738/ https://ncbi.nlm.nih.gov/pubmed/24744854 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/phy2.172 |
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