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Isolation and analysis of the 21q+ chromosome in the acute myelogenous leukemia 8;21 translocation: evidence that c-mos is not translocated.

Acute myelogenous leukemia (AML), subgroup M2, is associated with a nonrandom chromosomal translocation, t(8;21)(q22,q22). The oncogene c-mos also has been localized to the q22 band on chromosome 8. There is also evidence that genes on chromosome 21 may be important in the development of leukemia. T...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Drabkin, H A, Diaz, M, Bradley, C M, Le Beau, M M, Rowley, J D, Patterson, D
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1985
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397059/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2982159/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.2.464
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