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Direct Gene Transfer of Adenoviral-mediated Interferon α into Human Bladder Cancer Cells but Not the Bystander Factors Produced Induces Endoplasmic Reticulum Stress- Related Cytotoxicity
We have previously shown that adenoviral-mediated interferon α (Ad-IFNα) is cytotoxic both to cells that are sensitive to recombinant interferon (IFNα) and to cells which are resistant to IFNα. The cancer cell-specific cytotoxic effects of Ad-IFNα involve three different mechanisms: 1. The direct ef...
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| Hoofdauteurs: | , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2010
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3970572/ https://ncbi.nlm.nih.gov/pubmed/21183949 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2010.76 |
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