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N-WASP-directed actin polymerization activates Cas phosphorylation and lamellipodium spreading
Tyrosine phosphorylation of the substrate domain of Cas (CasSD) correlates with increased cell migration in healthy and diseased cells. Here, we address the mechanism leading to the phosphorylation of CasSD in the context of fibronectin-induced early spreading of fibroblasts. We have previously demo...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The Company of Biologists
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3970555/ https://ncbi.nlm.nih.gov/pubmed/24481817 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.134692 |
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