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Microvesicles containing miRNAs promote muscle cell death in cancer cachexia via TLR7

MicroRNAs (miRNAs) are small, noncoding RNAs that regulate gene expression and, in cancers, are often packaged within secreted microvesicles. The cachexia syndrome is a debilitating state of cancer that predominantly results from the loss of skeletal muscle mass, which is in part associated with apo...

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Bibliografski detalji
Glavni autori: He, Wei A., Calore, Federica, Londhe, Priya, Canella, Alessandro, Guttridge, Denis C., Croce, Carlo M.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3970508/
https://ncbi.nlm.nih.gov/pubmed/24616506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1402714111
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