Phospholipid Binding Lowers Immunogenicity of Human Recombinant Factor VIII in von Willebrand Factor Knockout Mice

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• Phospholipid Binding Improves Plasma Survival of Factor VIII
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• Native-like aggregates of Factor VIII (FVIII) are immunogenic von Willebrand Factor deficient and hemophilia A mice
  per: Pisal, Dipak S., et al.
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• Interaction of factor VIII-von Willebrand Factor with phospholipid vesicles.
  per: Andersson, L O, et al.
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• Role of Glycosylation in Conformational Stability, Activity, Macromolecular Interaction and Immunogenicity of Recombinant Human Factor VIII
  per: Kosloski, Matthew P., et al.
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  per: Kosloski, Matthew P., et al.
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