Caffeine restores myocardial cytochrome oxidase activity and improves cardiac function during sepsis

OBJECTIVE: Impaired mitochondrial function is a potential cause of sepsis-associated myocardial depression. Cytochrome oxidase (CcOX), the terminal oxidase of the electron transport chain, is inhibited in the septic heart. Caffeine increases CcOX activity by increasing cyclic adenosine monophosphate...

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Detaylı Bibliyografya
Asıl Yazarlar: Verma, Richa, Huang, Zhishan, Deutschman, Clifford S., Levy, Richard J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3970220/
https://ncbi.nlm.nih.gov/pubmed/19242342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0b013e31819cecd6
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