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Caffeine restores myocardial cytochrome oxidase activity and improves cardiac function during sepsis
OBJECTIVE: Impaired mitochondrial function is a potential cause of sepsis-associated myocardial depression. Cytochrome oxidase (CcOX), the terminal oxidase of the electron transport chain, is inhibited in the septic heart. Caffeine increases CcOX activity by increasing cyclic adenosine monophosphate...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3970220/ https://ncbi.nlm.nih.gov/pubmed/19242342 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0b013e31819cecd6 |
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