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Calmodulin binding to the cytoskeletal neuronal calmodulin-dependent protein kinase is regulated by autophosphorylation.

A brain cytoskeletal preparation that is highly enriched in calmodulin-dependent protein kinase facilitated the study of the binding of 125I-labeled calmodulin to the native enzyme. The binding was specific, saturable, Ca2+-dependent, and inhibited by trifluoperazine. Stoichiometric analysis reveale...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: LeVine, H, Sahyoun, N E, Cuatrecasas, P
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1985
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397022/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3855553/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.2.287
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