Functional reconstitution of the purified brain sodium channel in planar lipid bilayers.

The ion conduction and voltage dependence of sodium channels purified from rat brain were investigated in planar lipid bilayers in the presence of batrachotoxin. Single channel currents are clearly resolved. Channel opening is voltage dependent and favored by depolarization. The voltage at which the...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Hartshorne, R P, Keller, B U, Talvenheimo, J A, Catterall, W A, Montal, M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1985
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397008/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2578662/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.1.240
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