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Glucose increases the synthesis of lipoxygenase-mediated metabolites of arachidonic acid in intact rat islets.

Previous studies suggested that products of a 12-lipoxygenase pathway in the pancreatic islet may promote insulin release. To determine whether glucose augments the production of such metabolites, intact rat islets prelabeled with [3H]arachidonate were stimulated with glucose, and 12-hydroxy-5,8,10,...

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Pubblicato in:Proc Natl Acad Sci U S A
Autore principale: Metz, S A
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1985
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC396999/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3918302/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.1.198
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