The α(1) adrenoceptor antagonist prazosin enhances sleep continuity in fear-conditioned Wistar-Kyoto rats

Fragmentation of rapid eye movement sleep (REMS) is well described in individuals with posttraumatic stress disorder (PTSD) and likely has significant functional consequences. Fear-conditioned rodents may offer an attractive model of the changes in sleep that characterize PTSD. Following fear condit...

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Main Authors: Laitman, Benjamin M., Gajewski, Nicholas D., Mann, Graziella L., Kubin, Leszek, Morrison, Adrian R., Ross, Richard J.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969852/
https://ncbi.nlm.nih.gov/pubmed/24246572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pnpbp.2013.11.004
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