Genetic analysis of beta-adrenergic receptor internalization and down-regulation.

We have used wild-type and variants of the T-lymphoma cell line S49 to explore internalization and down-regulation of adenylate cyclase-linked beta-adrenergic receptors. Internalization was defined by the loss in "surface receptors" detected at 4 degrees C on intact cells by the antagonist...

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Bibliographic Details
Main Authors: Mahan, L C, Koachman, A M, Insel, P A
Format: Artigo
Language:Inglês
Published: 1985
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC396985/
https://ncbi.nlm.nih.gov/pubmed/2982140
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