A MALDI Imaging Mass Spectrometry Workflow for Spatial Profiling Analysis of N-linked Glycan Expression in Tissues

A new Matrix Assisted Laser Desorption Ionization Imaging Mass Spectrometry (MALDI-IMS) method to spatially profile the location and distribution of multiple N-linked glycan species in tissues is described. Application of an endoglycosidase, peptide N-glycosidase F (PNGaseF), directly on tissues fol...

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Hauptverfasser: Powers, Thomas W., Jones, E. Ellen, Betesh, Lucy R., Romano, Patrick, Gao, Peng, Copland, John A., Mehta, Anand S., Drake, Richard R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969840/
https://ncbi.nlm.nih.gov/pubmed/24050758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac402108x
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