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CXCL12 Enhances Human Neural Progenitor Cell Survival through a CXCR7- and CXCR4- mediated Endocytotic Signaling Pathway

Chemokine CXCL12 is widely expressed in the central nervous system (CNS) and essential for the proper functions of human neural progenitor cells (hNPCs). Although CXCL12 is known to function through its receptor CXCR4, recent data have suggested that CXCL12 binds to chemokine receptor CXCR7 with hig...

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Bibliographic Details
Main Authors: Zhu, Bing, Xu, Dongsheng, Deng, Xiaobei, Chen, Qiang, Huang, Yunlong, Peng, Hui, Li, Yuju, Jia, Beibei, Thoreson, Wallace B., Ding, Wenjun, Ding, Jianqing, Zhao, Lixia, Wang, Yi, Wavrin, Kristin Leland, Duan, Shumin, Zheng, Jialin
Format: Artigo
Language:Inglês
Published: 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969741/
https://ncbi.nlm.nih.gov/pubmed/22987307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1239
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