N(6)-isopentenyladenosine and analogs activate the NRF2-mediated antioxidant response

N(6)-isopentenyladenosine (i(6)A), a naturally occurring modified nucleoside, inhibits the proliferation of human tumor cell lines in vitro, but its mechanism of action remains unclear. Treatment of MCF7 human breast adenocarcinoma cells with i(6)A or with three synthetic analogs (allyl(6)A, benzyl(...

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Detalhes bibliográficos
Main Authors: Dassano, Alice, Mancuso, Mariateresa, Giardullo, Paola, Cecco, Loris De, Ciuffreda, Pierangela, Santaniello, Enzo, Saran, Anna, Dragani, Tommaso A., Colombo, Francesca
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969604/
https://ncbi.nlm.nih.gov/pubmed/24688894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2014.03.001
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