HIV Infection in Uncircumcised Men Is Associated With Altered CD8 T-cell Function But Normal CD4 T-cell Numbers in the Foreskin

Background. Human immunodeficiency virus (HIV)–infected (HIV+) men are more susceptible to sexually transmitted infections, and may be superinfected by HIV. We hypothesized that HIV induces immune alterations in the foreskin that may impact the subsequent acquisition/clearance of genital coinfection...

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Detalhes bibliográficos
Main Authors: Prodger, Jessica L., Hirbod, Taha, Gray, Ronald, Kigozi, Godfrey, Nalugoda, Fred, Galiwango, Ronald, Reynolds, Steven J., Huibner, Sanja, Wawer, Maria J., Serwadda, David, Kaul, Rupert, Nehemiah, Kighoma, Denis, Tumuramye, Emma, Mbagiira, John-Bosco, Kubaawo, Yahaya, Isabirye, Patrick, Mulema, James, Teba, Boru, Atukunda, Herbert, Mayengo, Mary, Nakafeero, Stephen, Mugamba, Mary, Nakyeyune, Margaret, Anyokorit, Deo, Male, Dan, Kayiwa, Sarah, Kalibbala, Lawrence, Lubyayi, Joseph, Otobi Ouma, Moses, Kakanga, Baptist, Okech John, Grace, Okello, Gerald, Aluma, Ivan, Ssebugenyi, Ambrose, Balikudembe
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969543/
https://ncbi.nlm.nih.gov/pubmed/24277744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jit644
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