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Encapsulation of Acetylshikonin by Polyamidoamine Dendrimers for Preparing Prominent Nanoparticles

Acetylshikonin (AS) has demonstrated antitumor potential. However, the development of therapeutic applications utilizing AS is inhibited by its poor solubility in water. In the present work, polyamidoamine (PAMAM) dendrimers and their PEGylated derivatives were employed to increase the solubility of...

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Detalhes bibliográficos
Main Authors: Peng, Jianqing, Zhou, Wen, Xia, Xinyi, Qi, Xiaole, Sun, Luan, Wang, Min, Wu, Zhenghong, Li, Zhengrong
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969479/
https://ncbi.nlm.nih.gov/pubmed/24449188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-014-0074-2
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