Cyclotide Structure–Activity Relationships: Qualitative and Quantitative Approaches Linking Cytotoxic and Anthelmintic Activity to the Clustering of Physicochemical Forces

Cyclotides are a family of plant-derived proteins that are characterized by a cyclic backbone and a knotted disulfide topology. Their cyclic cystine knot (CCK) motif makes them exceptionally resistant to thermal, chemical, and enzymatic degradation. Cyclotides exert much of their biological activity...

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Detaylı Bibliyografya
Asıl Yazarlar: Park, Sungkyu, Strömstedt, Adam A., Göransson, Ulf
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2014
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969350/
https://ncbi.nlm.nih.gov/pubmed/24682019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0091430
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