Identification of a BET family Bromodomain / Casein Kinase II / TAF-containing complex as a regulator of mitotic condensin function

Condensin is a central regulator of mitotic genome structure, with mutants showing poorly condensed chromosomes and profound segregation defects. Here we identify NCT complex, comprising the Nrc1 BET-family tandem bromodomain protein (SPAC631.02), Casein Kinase II (CKII) and several TAFs, as a regul...

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Main Authors: Kim, Hyun-Soo, Mukhopadhyay, Rituparna, Rothbart, Scott B., Silva, Andrea C., Vanoosthuyse, Vincent, Radovani, Ernest, Kislinger, Thomas, Roguev, Assen, Ryan, Colm J., Xu, Jiewei, Jahari, Harlizawati, Hardwick, Kevin G., Greenblatt, Jack F., Krogan, Nevan J., Fillingham, Jeffrey S., Strahl, Brian D., Bouhassira, Eric E., Edelmann, Winfried, Keogh, Michael-Christopher
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969266/
https://ncbi.nlm.nih.gov/pubmed/24565511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.01.029
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