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Biochemical and genetic characterization of Trypanosoma cruzi N-myristoyltransferase

Co- and post-translational N-myristoylation is known to play a role in the correct subcellular localization of specific proteins in eukaryotes. The enzyme that catalyses this reaction, NMT (N-myristoyltransferase), has been pharmacologically validated as a drug target in the African trypanosome, Try...

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Autori principali: Roberts, Adam J., Torrie, Leah S., Wyllie, Susan, Fairlamb, Alan H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Portland Press Ltd. 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969225/
https://ncbi.nlm.nih.gov/pubmed/24444291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20131033
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