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Protein Kinase CK-1 Inhibitors As New Potential Drugs for Amyotrophic Lateral Sclerosis

[Image: see text] Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease where motor neurons in cortex, brain stem, and spinal cord die progressively, resulting in muscle wasting, paralysis, and death. Currently, effective therapies for ALS are lacking; however, identification of patholo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Salado, Irene G., Redondo, Miriam, Bello, Murilo L., Perez, Concepción, Liachko, Nicole F., Kraemer, Brian C., Miguel, Laetitia, Lecourtois, Magalie, Gil, Carmen, Martinez, Ana, Perez, Daniel I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2014
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969104/
https://ncbi.nlm.nih.gov/pubmed/24592867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm500065f
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