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Andrographolide suppresses RANKL-induced osteoclastogenesis in vitro and prevents inflammatory bone loss in vivo

BACKGROUND AND PURPOSE: Osteoclasts play a pivotal role in diseases such as osteoporosis, rheumatoid arthritis and tumour bone metastasis. Thus, searching for natural compounds that may suppress osteoclast formation and/or function is promising for the treatment of osteoclast-related diseases. Here,...

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Podrobná bibliografie
Hlavní autoři: Zhai, Z J, Li, H W, Liu, G W, Qu, X H, Tian, B, Yan, W, Lin, Z, Tang, T T, Qin, A, Dai, K R
Médium: Artigo
Jazyk:Inglês
Vydáno: British Journal of Pharmacology 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969079/
https://ncbi.nlm.nih.gov/pubmed/24125472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12463
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