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Blocking Notch in Endothelial Cells Prevents Arteriovenous Fistula Failure Despite CKD

Neointima formation causes the failure of 60% of arteriovenous fistulas (AVFs) within 2 years. Neointima-forming mechanisms are controversial but possibly linked to excess proinflammatory responses and dysregulated Notch signaling. To identify how AVFs fail, we anastomosed the carotid artery to the...

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Autores principales: Wang, Yun, Liang, Anlin, Luo, Jinlong, Liang, Ming, Han, Guofeng, Mitch, William E., Cheng, Jizhong
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Nephrology 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3968498/
https://ncbi.nlm.nih.gov/pubmed/24480830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013050490
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