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Quantification of Small Molecule Drugs in Biological Tissue Sections by Imaging Mass Spectrometry Using Surrogate Tissue-Based Calibration Standards

Quantitative analysis of administered drugs in biological tissues is essential for understanding the mechanisms underlying their efficacy or toxicity. Imaging mass spectrometry (IMS) may allow the quantification of targeted drugs in tissue sections along with the visualization of their spatial distr...

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Bibliografiske detaljer
Main Authors: Takai, Nozomi, Tanaka, Yukari, Saji, Hideo
Format: Artigo
Sprog:Inglês
Udgivet: The Mass Spectrometry Society of Japan 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3968287/
https://ncbi.nlm.nih.gov/pubmed/24738041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5702/massspectrometry.A0025
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