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DNA Methyltransferase Inhibitors Improve the Effect of Chemotherapeutic Agents in SW48 and HT-29 Colorectal Cancer Cells

DNA methylation is an epigenetic phenomenon known to play an important role in the development and progression of human cancer. Enzyme responsible for this process is DNA methyltransferase 1 (DNMT1) that maintains an altered methylation pattern by copying it from parent to daughter DNA strands after...

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Autors principals: Flis, Sylwia, Gnyszka, Agnieszka, Flis, Krzysztof
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3967992/
https://ncbi.nlm.nih.gov/pubmed/24676085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092305
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