Katanin maintains meiotic metaphase chromosome alignment and spindle structure in vivo and has multiple effects on microtubules in vitro

Assembly of Caenorhabditis elegans female meiotic spindles requires both MEI-1 and MEI-2 subunits of the microtubule-severing ATPase katanin. Strong loss-of-function mutants assemble apolar intersecting microtubule arrays, whereas weaker mutants assemble bipolar meiotic spindles that are longer than...

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Bibliographic Details
Main Authors: McNally, Karen, Berg, Evan, Cortes, Daniel B., Hernandez, Veronica, Mains, Paul E., McNally, Francis J.
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2014
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3967969/
https://ncbi.nlm.nih.gov/pubmed/24501424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E13-12-0764
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