Basal-Supported Oral Therapy with Sitagliptin Counteracts Rebound Hyperglycemia Caused by GLP-1 Tachyphylaxis

Introduction. Treatment with a glucagon-like peptide 1 (GLP-1) analog fails in some patients due to rebound hyperglycemia caused by tachyphylaxis (GLP-1 tachyphylaxis). We investigated the efficacy of basal-supported oral therapy (BOT) with insulin glargine and sitagliptin for counteracting GLP-1 ta...

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Bibliografiske detaljer
Main Authors: Meguro, Shu, Kawai, Toshihide, Matsuhashi, Tomohiro, Sano, Motoaki, Fukuda, Keiichi, Itoh, Hiroshi, Suzuki, Yoshihiko
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2014
Fag:
Clinical Study
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3967600/
https://ncbi.nlm.nih.gov/pubmed/24738001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/927317
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