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Fenretinide Targets Chronic Myeloid Leukemia Stem/Progenitor Cells by Regulation of Redox Signaling

Aims: We have recently shown that fenretinide preferentially targets CD34(+) cells of acute myeloid leukemia (AML), and here, we test whether this agent exerts the effect on CD34(+) cells of chronic myeloid leukemia (CML), which are refractory to imatinib. Results: As tested by colony-forming cell a...

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Hlavní autoři: Du, Yanzhi, Xia, Yuan, Pan, Xiaoling, Chen, Zi, Wang, Aihua, Wang, Kankan, Li, Junmin, Zhang, Ji
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc. 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3967369/
https://ncbi.nlm.nih.gov/pubmed/24021153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2012.4935
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