Metabolic activation of CaMKII by Coenzyme A

Active metabolism regulates oocyte cell death via calcium/calmodulin-dependent protein kinase II (CaMKII) mediated phosphorylation of caspase-2, but the link between metabolic activity and CaMKII is poorly understood. Here we identify coenzyme A (CoA) as the key metabolic signal that inhibits Xenopu...

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Bibliografiske detaljer
Main Authors: McCoy, Francis, Darbandi, Rashid, Lee, Hoi Chang, Bharatham, Kavitha, Moldoveanu, Tudor, Royappa, Grace, Dodd, Keela, Lin, Wenwei, Chen, Si-Ing, Tangallapally, Rajendra P, Kurokawa, Manabu, Lee, Richard E., Shelat, Anang, Chen, Taosheng, Green, Douglas R., Harris, Robert A., Lin, Sue-Hwa, Fissore, Rafael A., Colbran, Roger J., Nutt, Leta K.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3967247/
https://ncbi.nlm.nih.gov/pubmed/24095281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.08.043
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