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Dereplication Strategies for Targeted Isolation of New Antitrypanosomal Actinosporins A and B from a Marine Sponge Associated-Actinokineospora sp. EG49

High resolution Fourier transform mass spectrometry (HRFTMS) and nuclear magnetic resonance (NMR) spectroscopy were employed as complementary metabolomic tools to dereplicate the chemical profile of the new and antitrypanosomally active sponge-associated bacterium Actinokineospora sp. EG49 extract....

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Detalhes bibliográficos
Main Authors: Abdelmohsen, Usama Ramadan, Cheng, Cheng, Viegelmann, Christina, Zhang, Tong, Grkovic, Tanja, Ahmed, Safwat, Quinn, Ronald J., Hentschel, Ute, Edrada-Ebel, RuAngelie
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3967206/
https://ncbi.nlm.nih.gov/pubmed/24663112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md12031220
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