Strong genetic evidence for a selective influence of GABA(A) receptors on a component of the bipolar disorder phenotype

Despite compelling evidence for a major genetic contribution to risk of bipolar mood disorder, conclusive evidence implicating specific genes or pathophysiological systems has proved elusive. In part this is likely to be related to the unknown validity of current phenotype definitions and consequent...

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Main Authors: Craddock, Nick, Jones, Lisa, Jones, Ian R, Kirov, George, Green, Elaine K, Grozeva, Detelina, Moskvina, Valentina, Nikolov, Ivan, Hamshere, Marian L, Vukcevic, Damjan, Caesar, Sian, Gordon-Smith, Katharine, Fraser, Christine, Russell, Ellie, Norton, Nadine, Breen, Gerome, Clair, David St, Collier, David A, Young, Allan H, Ferrier, I Nicol, Farmer, Anne, McGuffin, Peter, Holmans, Peter A, Donnelly, Peter, Owen, Michael J, O’Donovan, Michael C
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3967096/
https://ncbi.nlm.nih.gov/pubmed/19078961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2008.66
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