Exogenous t-PA Administration Increases Hippocampal Mature BDNF Levels. Plasmin- or NMDA-Dependent Mechanism?

Brain-derived neurotrophic factor (BDNF) through TrkB activation is central for brain functioning. Since the demonstration that plasmin is able to process pro-BDNF to mature BDNF and that these two forms have opposite effects on neuronal survival and plasticity, a particular attention has been paid...

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Bibliografische gegevens
Hoofdauteurs: Rodier, Marion, Prigent-Tessier, Anne, Béjot, Yannick, Jacquin, Agnès, Mossiat, Claude, Marie, Christine, Garnier, Philippe
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2014
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3966802/
https://ncbi.nlm.nih.gov/pubmed/24670989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092416
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