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A peptide-free, liposome-based oligosaccharide vaccine, adjuvanted with a natural killer T cell antigen, generates robust antibody responses in vivo

Due to the prevalence of oligo- and polysaccharides on the surfaces of pathogenic organisms, carbohydrates are primary targets for recognition by antibodies generated by the immune systems of higher organisms. Consequently, substantial effort has been expended in efforts to develop vaccines based on...

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Detalhes bibliográficos
Main Authors: Deng, S., Bai, L., Reboulet, R., Matthew, R., Engler, D. A., Teyton, L., Bendelac, A., Savage, P. B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3966715/
https://ncbi.nlm.nih.gov/pubmed/24683450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C3SC53471E
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