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Cerebellar Purkinje cell activity drives motor learning

The climbing fiber input to the cerebellar cortex is thought to provide instructive signals that drive the induction of motor skill learning. We found that optogenetic activation of Purkinje cells, the sole output neurons of the cerebellar cortex, can also drive motor learning in mice. This dual con...

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Detalhes bibliográficos
Main Authors: Nguyen-Vu, T.D.Barbara, Kimpo, Rhea R, Rinaldi, Jacob M, Kohli, Arunima, Zeng, Hongkui, Deisseroth, Karl, Raymond, Jennifer L
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3966616/
https://ncbi.nlm.nih.gov/pubmed/24162651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3576
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