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Reactive astrocytes promote adhesive interactions between brain endothelium and endothelial progenitor cells via HMGB1 and beta-2 integrin signaling

Endothelial progenitor cells (EPCs) may contribute to neurovascular repair after stroke and neurodegeneration. A key step in this process should involve adhesive interactions between EPCs and the targeted cerebral endothelium. Here, we tested the hypothesis that reactive astrocytes may play a critic...

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Autors principals: Hayakawa, Kazuhide, Pham, Loc-Duyen D., Arai, Ken, Lo, Eng H.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3966549/
https://ncbi.nlm.nih.gov/pubmed/24480450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.scr.2013.12.008
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