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Nitrite Induces the Extravasation of Iron Oxide Nanoparticles in Hypoxic Tumor Tissue

Nitrite undergoes reconversion to nitric oxide (NO) under conditions characteristic of the tumor microenvironment, such as hypoxia and low pH. This selective conversion of nitrite into NO in tumor tissue has led to the possibility of using nitrite to enhance drug delivery and radiation response. In...

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Bibliografski detalji
Glavni autori: Mistry, Nilesh, Stokes, Ashley M, Van Gambrell, James, Quarles, Christopher Chad
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3966547/
https://ncbi.nlm.nih.gov/pubmed/24470164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nbm.3078
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