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The Ca(2+)-activated K(+) current of human sperm is mediated by Slo3

Sperm are equipped with a unique set of ion channels that orchestrate fertilization. In mouse sperm, the principal K(+) current (I(KSper)) is carried by the Slo3 channel, which sets the membrane potential (V(m)) in a strongly pH(i)-dependent manner. Here, we show that I(KSper) in human sperm is acti...

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Detalhes bibliográficos
Main Authors: Brenker, Christoph, Zhou, Yu, Müller, Astrid, Echeverry, Fabio Andres, Trötschel, Christian, Poetsch, Ansgar, Xia, Xiao-Ming, Bönigk, Wolfgang, Lingle, Christopher J, Kaupp, U Benjamin, Strünker, Timo
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3966514/
https://ncbi.nlm.nih.gov/pubmed/24670955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.01438
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