Nanoparticle Shape Improves Delivery: Rational Coarse Grain Molecular Dynamics (rCG-MD) of Taxol in Worm-Like PEG-PCL Micelles

Nanoparticle shape can improve drug delivery, based in part on recent findings that flexible, worm-like nanocarriers (Worms) increase the amount of drug delivered to tumors and shrink the tumors more effectively than spherical micelles (Spheres). Here, all-atom molecular dynamics (MD) simulations ar...

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Hlavní autoři: Loverde, Sharon M., Klein, Michael L., Discher, Dennis E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3966472/
https://ncbi.nlm.nih.gov/pubmed/22105885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adma.201103192
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