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Association of proinflammatory cytokines and islet resident leucocytes with islet dysfunction in type 2 diabetes

AIMS/HYPOTHESIS: Chronic inflammation in type 2 diabetes is proposed to affect islets as well as insulin target organs. However, the nature of islet inflammation and its effects on islet function in type 2 diabetes remain unclear. Moreover, the immune cell profiles of human islets in healthy and typ...

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Detalhes bibliográficos
Main Authors: Butcher, Matthew J., Hallinger, Daniel, Garcia, Eden, Machida, Yui, Chakrabarti, Swarup, Nadler, Jerry, Galkina, Elena V., Imai, Yumi
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3966210/
https://ncbi.nlm.nih.gov/pubmed/24429578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-013-3116-5
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