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The autism and schizophrenia associated gene CYFIP1 is critical for the maintenance of dendritic complexity and the stabilization of mature spines

Copy number variation (CNV) at the 15q11.2 region has been identified as a significant risk locus for neurological and neuropsychiatric conditions such as schizophrenia (SCZ) and autism spectrum disorder (ASD). However, the individual roles for genes at this locus in nervous system development, func...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Pathania, M, Davenport, E C, Muir, J, Sheehan, D F, López-Doménech, G, Kittler, J T
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3966042/
https://ncbi.nlm.nih.gov/pubmed/24667445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2014.16
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