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Regulator of fatty acid metabolism, acetyl CoA carboxylase 1 (ACC1), controls T cell immunity

Fatty acids (FA) are essential constituents of cell membranes, signaling molecules, and bioenergetic substrates. As CD8(+) T cells undergo both functional and metabolic changes during activation and differentiation, dynamic changes in FA metabolism also occur. However, the contributions of de novo l...

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Main Authors: Lee, JangEun, Walsh, Matthew C., Hoehn, Kyle L., James, David E., Wherry, E. John, Choi, Yongwon
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3965631/
https://ncbi.nlm.nih.gov/pubmed/24567531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302985
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