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A vaccine formulated with a combination of TLR-2 and TLR-9 adjuvants and the recombinant major outer membrane protein elicits a robust immune response and significant protection against a C. muridarum challenge

Chlamydia trachomatis is the most common sexually transmitted bacterial pathogen in the World and there is a need for a vaccine. To enhance the immunogenicity of a vaccine formulated with the Chlamydia muridarum (Cm) mouse pneumonitis recombinant major outer membrane protein (MOMP), we used combinat...

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Hlavní autoři: Cheng, Chunmei, Pal, Sukumar, Tifrea, Delia, Jia, Zhenyu, de la Maza, Luis M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3965591/
https://ncbi.nlm.nih.gov/pubmed/24291713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.micinf.2013.11.009
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