Light-Mediated Kinetic Control Reveals the Temporal Effect of the Raf/MEK/ERK Pathway in PC12 Cell Neurite Outgrowth

It has been proposed that differential activation kinetics allows cells to use a common set of signaling pathways to specify distinct cellular outcomes. For example, nerve growth factor (NGF) and epidermal growth factor (EGF) induce different activation kinetics of the Raf/MEK/ERK signaling pathway...

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Detalhes bibliográficos
Main Authors: Zhang, Kai, Duan, Liting, Ong, Qunxiang, Lin, Ziliang, Varman, Pooja Mahendra, Sung, Kijung, Cui, Bianxiao
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3965503/
https://ncbi.nlm.nih.gov/pubmed/24667437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092917
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