Bovine Exome Sequence Analysis and Targeted SNP Genotyping of Recessive Fertility Defects BH1, HH2, and HH3 Reveal a Putative Causative Mutation in SMC2 for HH3

The recent discovery of bovine haplotypes with negative effects on fertility in the Brown Swiss, Holstein, and Jersey breeds has allowed producers to identify carrier animals using commercial single nucleotide polymorphism (SNP) genotyping assays. This study was devised to identify the causative mut...

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Hauptverfasser: McClure, Matthew C., Bickhart, Derek, Null, Dan, VanRaden, Paul, Xu, Lingyang, Wiggans, George, Liu, George, Schroeder, Steve, Glasscock, Jarret, Armstrong, Jon, Cole, John B., Van Tassell, Curtis P., Sonstegard, Tad S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3965462/
https://ncbi.nlm.nih.gov/pubmed/24667746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092769
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