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A Ring Distortion Strategy to Construct Stereochemically Complex and Structurally Diverse Compounds from Natural Products
High-throughput screening is the dominant method to identify lead compounds in drug discovery. As such, the makeup of screening libraries will largely dictate the biological targets that can be modulated and the therapeutics that can be developed. Unfortunately, most compound screening collections c...
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| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3965367/ https://ncbi.nlm.nih.gov/pubmed/23422561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchem.1549 |
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