Phase III Randomized, Placebo-Controlled, Double-Blind Study of Intravenous Calcium and Magnesium to Prevent Oxaliplatin-Induced Sensory Neurotoxicity (N08CB/Alliance)

PURPOSE: Cumulative neurotoxicity is a prominent toxicity of oxaliplatin-based therapy. Intravenous calcium and magnesium have been extensively used to reduce oxaliplatin-induced neurotoxicity. This trial was designed to definitively test whether calcium/magnesium decreases oxaliplatin-related neuro...

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Detalhes bibliográficos
Main Authors: Loprinzi, Charles L., Qin, Rui, Dakhil, Shaker R., Fehrenbacher, Louis, Flynn, Kathleen A., Atherton, Pamela, Seisler, Drew, Qamar, Rubina, Lewis, Grant C., Grothey, Axel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2014
Assuntos:
ORIGINAL REPORTS
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3965262/
https://ncbi.nlm.nih.gov/pubmed/24297951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2013.52.0536
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