Intravitreal and Subconjunctival Melphalan for Retinoblastoma in Transgenic Mice

Purpose. To measure the chemotherapeutic effects of focal melphalan (intravitreal and subconjunctival) on tumor burden, hypoxia, and vasculature in LHBETATAG murine retinoblastoma model. Methods. LHBETATAG transgenic mice were treated with a single 1 mcg intravitreal injection of melphalan, 100 mcg...

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Bibliographic Details
Main Authors: Shah, Nisha V., Pham, D. G., Murray, T. G., Decatur, C., Hernandez, E., Shah, Nikesh N., Cavalcante, M., Houston, S. K.
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3964900/
https://ncbi.nlm.nih.gov/pubmed/24734170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/829879
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