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Cardiac fibroblast-derived 3D extracellular matrix seeded with mesenchymal stem cells as a novel device to transfer cells to the ischemic myocardium
PURPOSE: Demonstrate a novel manufacturing method to generate extracellular matrix scaffolds from cardiac fibroblasts (CF-ECM) as a therapeutic mesenchymal stem cell-transfer device. MATERIALS AND METHODS: Rat CF were cultured at high-density (~1.6×10(5)/cm(2)) for 10–14 days. Cell sheets were remov...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3964807/ https://ncbi.nlm.nih.gov/pubmed/24683428 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13239-013-0167-1 |
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